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Authors
Affiliations
1 Jyothishmathi Institute of Pharmaceutical Science, Ramakrishna colony, Karimnagar, AP, IN
2 Talla Padmavathi College of Pharmacy, ours, Karimabad, Warangal, AP, IN
3 Procadence Institute of Pharmaceutical Sciences. Gajwel, Medak,. A.P, IN
4 Jyothishmathi Institute of Pharmaceutical Science, Ramakrishna colony, Karimnagar, AP
Source
Asian Journal of Research in Chemistry, Vol 6, No 8 (2013), Pagination: 731-734
Abstract
An efficient method for synthesis of 4 substituted 5 -phenyl - 3- mercapto -1, 2, 4 -triazole, by the mode of ring cleavage of oxadiazoles, nucleophiles are readily attack 5-phenyl 1,3,4- oxadiazole-2 - thiols and they are cleaved by acids and basis, in a reaction, which is the reverse of the ring closure, many nucleophilic ring cleavage reaction are followed by recyclization to give different heterocyclics, we were sysnthsized 5 different compounds and characterized its physical data, spectral analysis by IR and these compounds screened for possible CNS activity.
Keywords
Triazoles, Oxadiazole, Grass Behavior Study, Locomotor Activity
References
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